The four selected participants will work directly on the development and execution of the trial.
Responsibilities include:
Developing the pilot clinical study protocol.
Conducting the literature review supporting the scientific rationale.
Preparing study forms, case-report forms, consent documents, data dictionaries, and operating procedures.
Preparing and submitting the protocol to IMAT Oncomédica Auna in Montería, Colombia and its Ethics Committee.
Supporting required revisions arising from institutional and ethics review.
Preparing the prospective registration for ClinicalTrials.gov.
Ensuring consistency between the approved protocol, ethics documents, statistical analysis plan, and trial registry.
Organizing study logistics before prospective enrollment.
Coordinating with Dr. Agamenón Quintero Villarreal and his ICU staff the trial logistics and data colelction.
Supporting prospective data collection from November 2026 through February 2027.
Using the project's Zoom-based telephone system for protocol-authorized follow-up with parents or guardians.
Recording adherence to feeding recommendations using standardized procedures.
Documenting protocol deviations and missed follow-up.
Ensuring written informed consent from the before or legal guardian before study participation. This includes assessing the trial staff compliance with regulatory forms.
Conducting database quality control.
Performing statistical analysis under Jorge Racedo's supervision.
Participating substantially in interpretation, manuscript preparation, manuscript revision, and responses to reviewers.
A telephone contact will be available to call internationally to the trial facility, yet participants will not be authorized to enroll in clinical decision-making or activities or any other outside the trial execution. Contact with patients or legal guardians or caregivers will not be allowed unless Dr. Agamenón Quintero Villarreal explicitly require support and Jorge Racedo further approves it.
The project is expected to generate:
Clinical Trial
Critical Care Medicine, Clinical Epidemiology
Jorge Racedo at microscopIA, External Clinicians, Dr. Agamenon Quintero Villarreal at IMAT Oncomédica Auna
Applicants may include physicians, medical students, biomedical or health researchers, epidemiologists, and other candidates with a relevant clinical or research background.
Applicants must:
Be fluent in Spanish.
Have documented training or formal coursework in biostatistics.
Be able to contribute to statistical analysis under Jorge Racedo's supervision.
Have strong attention to research documentation and participant confidentiality.
Be available during the protocol-development phase and the prospective data-collection period.
Be able to collaborate with pediatric ophthalmology and retina specialists.
Have reliable internet access for remote project activities.
Availability for approximately 3–5 hours per week.
Previous exposure to critical care, clinical trials, epidemiology, health economics, or photobiology is desirable.
Any Country
Protocol Development, Ethics Submission, Trial Registration, Informed Consent, Parent Follow-Up, Clinical Data Collection, Data Curation, Data Validation, Data Quality Control, Biostatistical Analysis, Literature Review, Manuscript Preparation, Manuscript Revision, Conference Presentation, Poster Preparation, Response to Reviewers
4
Spanish
Clinical evidence already exists for several distinct forms of light-based intervention in intensive care, which reinforces the need to define this trial's intervention precisely.
A randomized controlled trial of dynamic high-intensity light in 734 intensive-care patients did not reduce intensive-care-acquired delirium, demonstrating both the feasibility of light intervention research in critical care and the importance of clinically relevant control conditions.
A separate randomized, triple-blind, sham-controlled trial of red and near-infrared photobiomodulation in 60 intensive-care patients reported shorter intensive care stay and improvements in muscle function and mobility. This represents a closer precedent if the planned intervention is photobiomodulation rather than environmental bright-light therapy.
Vitamin D should be treated as a prespecified biological variable rather than an assumed mechanism of benefit. Studies in critically ill patients have reported inconsistent associations between vitamin D interventions and mortality, mechanical ventilation, and length of stay.
Record from a Project with a Foundational Methodology
If the planned intervention is environmental or circadian light therapy:
Dynamic light application therapy to reduce the incidence and duration of delirium in intensive-care patients: a randomised controlled trial. PMID: 26895652.
If the planned intervention is red or near-infrared photobiomodulation:
Photobiomodulation therapy reduced the length of stay in intensive care unit and improved muscle function: a randomized, triple-blind, sham-controlled trial. PMID: 38262071.articipants will work under direct clinical and methodological supervision from Jorge Racedo and Dr. Agamenón Quintero Villarreal.
Training will cover:
Critical-care trial design.
Protocol development.
Ethics and consent.
ClinicalTrials.gov registration.
Outcome definition.
Mortality analysis.
Resource-utilization analysis.
Length-of-stay analysis.
Hospital expenditure analysis.
Data quality.
Biostatistical analysis.
Scientific writing.
28 de septiembre de 2026 a las 0:00:00
30 de septiembre de 2026
1 de octubre de 2026
28 de febrero de 2027
Each participant may report a maximum of two legitimate institutional affiliations.
Required format:
Department, Institution or Organization, City, CountrymicroscopIA will cover approved publication fees associated with the anticipated regional manuscript.
Participants will not be required to personally pay approved article-processing charges.
Memberships are reinvested to pay microscopIA staff (epidemiologists, engineers, data scientists) salaries and to cover the publication fees for the resulting manuscripts. This maintain our work neutral, financially self-sustainable, and without any existing conflict of interest to maintain rigor and integrity in evidence generation.